| 8/30 | A | Shadyside (8-4) | [7:27] | L | 7-33 | |
| 9/6 | H | Linsly (WV) (7-3) | [6:0] | L | 13-14 | |
| 9/13 | A | Union Local (0-10) | [4:15] | W | 50-7 | |
| 9/20 | H | St Clairsville (8-3) | [4:15] | L | 26-41 | |
| 9/27 | H | Harrison Central (4-6) | [5:17] | W | 50-7 | |
| 10/4 | H | East Liverpool (5-5) | [4:13] | W | 23-13 | |
| 10/11 | A | Indian Creek (10-2) | [4:13] | L | 7-21 | |
| 10/18 | H | Wheeling Central Catholic (WV) (6-4) | [7:0] | W | 27-13 | |
| 10/25 | A | Beaver Local (5-5) | [4:13] | W | 39-7 | |
| 11/2 | A | Bellaire (7-4) | [5:17] | W | 23-12 |