| 8/24 | H | Urbana (5-5) | [4:16] | W | 41-7 | |
| 8/31 | A | Madison-Plains (3-7) | [5:20] | W | 61-0 | |
| 9/7 | H | Washington (7-3) | [4:16] | W | 57-7 | |
| 9/14 | A | Liberty Union (2-8) | [5:19] | W | 56-13 | |
| 9/21 | H | Circleville (0-10) | [4:15] | W | 81-7 | |
| 9/28 | A | Columbus Academy (6-4) | [5:19] | W | 42-27 | |
| 10/5 | A | Grandview Heights (7-4) | [6:23] | W | 42-0 | |
| 10/12 | H | Bishop Ready (4-6) | [5:19] | W | 49-14 | |
| 10/19 | H | Bexley (1-9) | [4:15] | W | 56-0 | |
| 10/26 | A | Whitehall-Yearling (10-2) | [2:7] | L | 15-34 | |
| 11/3 | A | # Taft (8-2) | [4:16] | W | 37-21 | |
| 11/10 | N | # Clinton-Massie (10-2) | [4:16] | W | 28-7 | |
| 11/17 | N | # Wyoming (15-0) | [4:16] | L | 0-28 | |
| # - Ohio playoff game | ||||||