| 8/18 | A | St Xavier (7-5) | [I:4] | L | 0-10 | |
| 8/25 | H | Princeton (12-1) | [I:4] | L | 3-18 | |
| 9/1 | A | Fairfield (3-8) | [I:4] | W | 33-0 | |
| 9/8 | H | Middletown (3-8) | [I:4] | W | 35-0 | |
| 9/15 | A | Colerain (0-10) | [I:4] | W | 38-7 | |
| 9/22 | A | Sycamore (5-6) | [I:4] | W | 34-14 | |
| 9/29 | H | Oak Hills (5-6) | [I:4] | W | 59-7 | |
| 10/6 | A | Lakota East (1-9) | [I:4] | W | 34-0 | |
| 10/13 | H | Mason (7-6) | [I:4] | W | 10-7 | |
| 10/20 | A | Hamilton (8-4) | [I:4] | W | 42-14 | |
| 10/27 | H | # Western Hills (4-7) | [I:4] | W | 69-0 | |
| 11/3 | H | # Elder (7-5) | [I:4] | W | 24-14 | |
| 11/10 | N | # Princeton (12-1) | [I:4] | W | 19-7 | |
| 11/17 | N | # Archbishop Moeller (10-5) | [I:4] | L | 0-22 | |
| # - Ohio playoff game | ||||||