| 8/19 | A | Taylor (4-6) | [IV:16] | L | 0-20 | |
| 8/26 | H | Northwestern (1-9) | [V:20] | W | 28-6 | |
| 9/2 | A | West Jefferson (5-7) | [VI:23] | L | 20-43 | |
| 9/9 | H | West Liberty-Salem (6-6) | [VI:24] | L | 21-22 | |
| 9/16 | A | Triad (4-7) | [VI:24] | L | 7-26 | |
| 9/23 | H | Cedarville (5-6) | [VII:28] | L | 7-17 | |
| 9/30 | H | Southeastern Local (7-5) | [VII:28] | W | 14-12 | |
| 10/7 | A | Catholic Central (7-5) | [VII:28] | W | 34-3 | |
| 10/14 | A | Madison-Plains (0-10) | [VI:24] | W | 74-0 | |
| 10/21 | H | Greeneview (9-2) | [V:20] | L | 3-42 | |
| 10/28 | A | # Milton-Union (13-1) | [V:20] | L | 0-49 | |
| # - Ohio playoff game | ||||||