| 8/19 | H | Meigs (2-8) | [V:19] | W | 39-0 | |
| 8/25 | A | Athens (6-5) | [III:11] | W | 30-0 | |
| 9/1 | A | Point Pleasant (WV) (5-5) | [IV] | W | 42-12 | |
| 9/8 | H | Chesapeake (3-7) | [V:19] | W | 47-21 | |
| 9/15 | H | Portsmouth (6-6) | [V:19] | W | 50-18 | |
| 9/22 | A | Fairland (9-2) | [V:19] | L | 35-40 | |
| 9/29 | H | Coal Grove (4-7) | [VI:23] | W | 28-12 | |
| 10/6 | A | Rock Hill (4-7) | [VI:23] | W | 44-7 | |
| 10/13 | H | Ironton (11-2) | [V:19] | L | 17-27 | |
| 10/20 | A | South Point (5-6) | [V:19] | W | 28-0 | |
| 10/27 | H | # Vinton County (9-2) | [IV:15] | W | 34-6 | |
| 11/3 | A | # Sheridan (12-2) | [IV:15] | L | 0-42 | |
| # - Ohio playoff game | ||||||