| 8/25 | H | Meigs (6-4) | [3:12] | W | 18-6 | |
| 9/1 | A | Dawson-Bryant (3-6) | [5:20] | W | 40-6 | |
| 9/8 | A | Ironton (10-2) | [4:15] | L | 10-26 | |
| 9/15 | H | Marietta (3-7) | [2:7] | W | 49-14 | |
| 9/22 | A | Warren (4-6) | [2:7] | W | 23-14 | |
| 9/29 | A | River Valley (0-10) | [4:15] | W | 41-0 | |
| 10/6 | H | Athens (2-8) | [2:7] | W | 35-0 | |
| 10/13 | H | Logan (12-1) | [1:3] | L | 7-31 | |
| 10/20 | H | Point Pleasant (WV) (7-3) | [3:0] | W | 34-13 | |
| 10/27 | A | Jackson (8-3) | [3:12] | W | 35-21 | |
| 11/4 | H | # Purcell Marian (8-4) | [3:12] | L | 12-41 | |
| # - Ohio playoff game | ||||||