| 8/27 | A | Meigs (6-4) | [3:11] | W | 21-6 | |
| 9/3 | H | Coal Grove (1-9) | [5:19] | W | 42-8 | |
| 9/10 | H | Ironton (10-4) | [4:16] | L | 6-44 | |
| 9/17 | H | Warren (6-4) | [3:11] | W | 35-9 | |
| 9/24 | H | River Valley (0-10) | [4:16] | W | 43-7 | |
| 10/1 | A | Athens (1-9) | [2:8] | W | 39-7 | |
| 10/8 | A | Logan (9-2) | [1:3] | L | 15-48 | |
| 10/15 | A | Point Pleasant (WV) (5-5) | W | 10-7 | ||
| 10/22 | H | Jackson (8-3) | [3:12] | W | 24-6 | |
| 10/29 | A | Marietta (6-4) | [2:8] | W | 21-0 | |
| 11/5 | A | # Jackson (8-3) | [3:12] | W | 35-7 | |
| 11/12 | N | # New Richmond (9-3) | [3:12] | W | 47-12 | |
| 11/19 | N | # Chaminade Julienne (11-3) | [3:12] | L | 6-43 | |
| # - Ohio playoff game | ||||||