| 8/25 | H | Buffalo (Putnam) (WV) (2-8) | [6:0] | W | 51-6 | |
| 9/1 | H | Valley (3-7) | [6:23] | W | 38-20 | |
| 9/8 | H | Portsmouth West (10-2) | [5:19] | L | 6-28 | |
| 9/15 | A | South Point (2-8) | [5:19] | W | 43-0 | |
| 9/22 | H | Chesapeake (4-6) | [5:19] | W | 27-7 | |
| 9/29 | A | Portsmouth (5-5) | [5:19] | W | 19-14 | |
| 10/6 | A | Gallia Academy (5-5) | [4:15] | W | 33-20 | |
| 10/13 | H | Ironton (4-6) | [5:19] | W | 28-7 | |
| 10/20 | H | Fairland (6-4) | [5:19] | W | 29-19 | |
| 10/27 | A | Rock Hill (4-6) | [5:19] | W | 28-7 | |
| 11/3 | H | # Shenandoah (8-3) | [6:23] | W | 7-6 | |
| 11/10 | N | # Southeastern (11-1) | [6:23] | W | 46-22 | |
| 11/17 | N | # Nelsonville-York (13-1) | [6:23] | L | 7-28 | |
| # - Ohio playoff game | ||||||