| 8/30 | H | Northmont (8-3) | [1:2] | W | 32-22 | |
| 9/6 | A | Chaminade-Julienne (6-5) | [5:18] | L | 55-58 | |
| 9/13 | A | Archbishop Alter (11-2) | [4:14] | W | 34-14 | |
| 9/26 | H | Winton Woods (9-3) | [2:6] | L | 34-41 | |
| 10/4 | A | Meadowdale (6-4) | [3:10] | W | 68-0 | |
| 10/12 | H | St Vincent-St Mary (15-0) | [3:7] | L | 12-41 | |
| 10/17 | H | Belmont (0-10) | [3:10] | W | 56-0 | |
| 10/25 | A | Dunbar (5-5) | [4:14] | W | 49-0 | |
| 11/2 | A | Ponitz Tech (3-7) | [3:10] | W | 56-0 | |
| 11/8 | A | # Western Brown (10-1) | [3:10] | W | 76-40 | |
| 11/15 | N | # Tippecanoe (12-1) | [3:10] | L | 13-30 | |
| # - Ohio playoff game | ||||||