| 8/28 | A | Anderson (9-3) | [II:8] | L | 22-29 | |
| 9/3 | H | Bishop Fenwick (3-6) | [III:12] | W | 44-0 | |
| 9/10 | A | St Francis DeSales (7-5) | [III:11] | W | 17-7 | |
| 9/17 | A | Harrison (4-6) | [II:8] | W | 42-10 | |
| 9/24 | A | Goshen (1-9) | [III:12] | W | 69-14 | |
| 10/1 | H | Western Brown (11-3) | [III:11] | W | 42-35 | |
| 10/8 | A | Batavia (1-8) | [IV:16] | W | 79-0 | |
| 10/15 | H | New Richmond (4-5) | [III:12] | W | 70-34 | |
| 10/22 | A | Wilmington (3-7) | [III:11] | W | 35-0 | |
| 10/29 | H | # Northridge (7-4) | [IV:16] | W | 55-13 | |
| 11/5 | H | # Waverly (9-2) | [IV:16] | W | 49-28 | |
| 11/12 | N | # Wyoming (12-1) | [IV:16] | W | 42-14 | |
| 11/19 | N | # Archbishop McNicholas (11-2) | [IV:16] | W | 28-27 | |
| 11/26 | N | # Bloom-Carroll (14-1) | [IV:15] | W | 24-21 | |
| 12/3 | N | # Ursuline (11-4) | [IV:13] | W | 29-28 | |
| # - Ohio playoff game | ||||||