| 8/18 | H | Eastmoor Academy (5-5) | [IV:15] | W | 35-0 | |
| 8/25 | H | Belmont (1-8) | [II:8] | W | 67-0 | |
| 9/1 | H | Bishop Hartley (10-3) | [IV:15] | L | 7-21 | |
| 9/8 | A | Franklin (2-8) | [III:12] | W | 34-28 | |
| 9/15 | A | Edgewood (4-7) | [II:8] | W | 28-7 | |
| 9/22 | A | Archbishop McNicholas (6-6) | [IV:16] | L | 0-35 | |
| 9/28 | H | Bishop Fenwick (5-5) | [IV:16] | W | 48-20 | |
| 10/6 | A | Archbishop Carroll (2-8) | [III:12] | W | 56-7 | |
| 10/13 | H | Badin (13-1) | [III:12] | L | 13-27 | |
| 10/20 | H | Archbishop Alter (12-4) | [IV:16] | L | 14-21 | |
| 10/27 | A | # Mount Healthy (8-3) | [III:12] | W | 35-28 | |
| 11/3 | A | # Tippecanoe (10-3) | [III:12] | L | 21-30 | |
| # - Ohio playoff game | ||||||