| 8/25 | A | Wheeling Central Catholic (WV) (6-4) | [7:0] | W | 35-14 | |
| 9/2 | H | Oak Glen (WV) (2-8) | [4:0] | W | 63-28 | |
| 9/8 | A | Western Reserve (8-3) | [6:21] | L | 33-43 | |
| 9/15 | A | South Harrison (WV) (9-1) | [6:0] | L | 14-48 | |
| 9/23 | H | John F Kennedy (4-7) | [7:25] | W | 39-23 | |
| 9/30 | H | Barnesville (3-7) | [6:23] | W | 46-0 | |
| 10/7 | H | Saint Mary's (NY) (4-4) | [6:0] | W | 47-14 | |
| 10/14 | H | Edison (2-8) | [5:17] | W | 49-13 | |
| 10/19 | A | Madonna (WV) (8-2) | [7:0] | W | 43-7 | |
| 10/27 | A | Fort Frye (10-2) | [6:23] | L | 13-49 | |
| 11/3 | A | # Southeastern (11-1) | [6:23] | L | 40-44 | |
| # - Ohio playoff game | ||||||