| 8/28 | A | Wheeling Central Catholic (WV) (9-1) | [6:0] | L | 28-39 | |
| 9/5 | H | Oak Glen (WV) (4-6) | [4:0] | W | 56-28 | |
| 9/12 | H | Weir (WV) (7-3) | [3:0] | L | 41-55 | |
| 9/19 | H | Toronto (10-2) | [7:23] | L | 0-36 | |
| 9/26 | H | John F Kennedy (11-2) | [7:23] | L | 28-38 | |
| 10/3 | A | Bellaire (2-8) | [6:21] | W | 40-14 | |
| 10/9 | A | Barnesville (7-3) | [6:21] | W | 13-12 | |
| 10/16 | A | Bishop Donahue (WV) (7-3) | [7:0] | W | 42-14 | |
| 10/24 | A | Madonna (WV) (2-8) | [7:0] | W | 48-7 | |
| 10/31 | H | St John Central (2-8) | [7:25] | W | 56-7 |