| 8/25 | H | Northwestern (2-8) | [3:12] | W | 42-6 | |
| 9/1 | A | Shawnee (6-4) | [3:12] | L | 6-24 | |
| 9/8 | H | Kenton Ridge (1-9) | [4:16] | W | 22-6 | |
| 9/15 | A | Miami East (4-6) | [5:20] | W | 13-12 | |
| 9/22 | H | Milton-Union (1-9) | [4:16] | L | 14-26 | |
| 9/29 | A | Lehman Catholic (7-4) | [5:20] | L | 7-62 | |
| 10/6 | H | Benjamin Logan (3-7) | [4:14] | L | 0-13 | |
| 10/13 | A | Tippecanoe (6-4) | [3:12] | L | 7-35 | |
| 10/20 | A | Versailles (5-5) | [5:20] | L | 21-46 | |
| 10/27 | H | Graham Local (8-2) | [3:12] | L | 13-16 |