| 8/18 | H | Buckeye Trail (4-6) | [VI:23] | W | 39-26 | |
| 8/25 | H | Waterford (8-5) | [VII:27] | W | 41-14 | |
| 9/1 | A | Wellsville (1-9) | [VII:25] | W | 49-7 | |
| 9/8 | H | Monroe Central (7-5) | [VII:27] | W | 48-26 | |
| 9/15 | A | Belpre (1-9) | [VI:23] | W | 49-0 | |
| 9/22 | H | Conotton Valley (4-7) | [VII:25] | W | 51-8 | |
| 9/29 | H | Barnesville (12-1) | [V:19] | L | 7-41 | |
| 10/6 | A | Fort Frye (10-3) | [VI:23] | L | 6-35 | |
| 10/13 | A | Toronto (9-2) | [VII:25] | L | 20-54 | |
| 10/20 | H | Shenandoah (3-7) | [VI:23] | W | 37-6 | |
| 10/27 | H | # Bridgeport (3-8) | [VII:27] | W | 41-14 | |
| 11/3 | H | # Notre Dame (8-4) | [VII:27] | W | 50-0 | |
| 11/10 | N | # Waterford (8-5) | [VII:27] | W | 20-13 | |
| 11/17 | N | # Eastern (12-2) | [VII:27] | W | 20-19 | |
| 11/24 | N | # Dalton (13-2) | [VII:25] | L | 7-55 | |
| # - Ohio playoff game | ||||||