| 8/20 | A | Beechcroft (7-4) | [III:11] | L | 6-24 | |
| 8/27 | H | Whetstone (2-7) | [II:7] | W | 36-8 | |
| 9/3 | A | Franklin Heights (0-8) | [II:8] | C* | cancelled | |
| 9/11 | A | Walnut Ridge (1-7) | [II:7] | C* | cancelled | |
| 9/16 | H | Marion-Franklin (4-6) | [IV:15] | L | 8-44 | |
| 9/24 | A | Tri-Valley (8-2) | [III:11] | L | 14-36 | |
| 9/24 | A | Africentric Early College (6-4) | [VI:23] | C* | cancelled | |
| 10/1 | A | Eastmoor Academy (7-4) | [III:11] | C* | cancelled | |
| 10/8 | H | Independence (5-6) | [II:7] | L | 22-40 | |
| 10/15 | A | South (7-4) | [III:11] | L | 0-73 | |
| 10/22 | H | West (0-9) | [II:8] | W | 50-20 | |
| * - game does not count in OHSAA rankings | ||||||