| 8/31 | A | O'Fallon (IL) (0-1) | W | 65-21 | ||
| 9/6 | A | Edwardsville (IL) (0-1) | W | 44-27 | ||
| 9/12 | A | Chaminade (0-1) | W | 56-26 | ||
| 9/20 | H | DeSmet (1-0) | L | 14-42 | ||
| 9/27 | A | St Louis University High (0-2) | W | 45-14 | ||
| 10/5 | H | Winton Woods (OH) (6-3) | [2:8] | W | 42-31 | |
| 10/11 | H | Vianney (0-1) | W | 49-7 | ||
| 10/18 | A | Rockhurst (1-0) | L | 14-31 | ||
| 10/25 | H | Belleville West (IL) (0-1) | W | 48-14 | ||
| 11/1 | H | St Louis University High (0-2) | W | 27-14 |