| 8/24 | H | Woodrow Wilson (2-8) | [3:9] | W | 35-8 | |
| 9/1 | A | St Ignatius (11-4) | [1:1] | L | 27-47 | |
| 9/7 | H | Chaney (10-2) | [2:5] | W | 10-7 | |
| 9/15 | A | Cardinal Mooney (1-9) | [4:13] | W | 42-7 | |
| 9/21 | H | Steubenville (8-3) | [3:11] | W | 52-0 | |
| 9/28 | H | Jackson (9-3) | [1:2] | W | 22-19 | |
| 10/5 | A | Warren G Harding (11-2) | [1:1] | L | 28-43 | |
| 10/12 | A | East Liverpool (7-3) | [2:5] | W | 56-0 | |
| 10/19 | H | Ursuline (3-7) | [4:13] | W | 31-27 | |
| 10/26 | H | Austintown-Fitch (3-7) | [1:1] | W | 30-0 | |
| 11/3 | A | # Warren G Harding (11-2) | [1:1] | L | 7-16 | |
| # - Ohio playoff game | ||||||