| 8/25 | H | Woodrow Wilson (2-8) | [3:11] | W | 56-7 | |
| 9/1 | H | St Ignatius (11-1) | [1:1] | L | 7-26 | |
| 9/8 | H | Chaney (10-1) | [2:5] | L | 20-42 | |
| 9/15 | H | Cardinal Mooney (5-5) | [4:13] | W | 21-15 | |
| 9/22 | A | Steubenville (7-3) | [3:11] | L | 6-14 | |
| 9/29 | A | Jackson (8-3) | [1:2] | L | 7-10 | |
| 10/6 | H | Warren G Harding (7-3) | [1:1] | W | 20-7 | |
| 10/13 | H | East Liverpool (7-3) | [2:7] | W | 41-21 | |
| 10/20 | A | Ursuline (14-1) | [4:13] | L | 22-43 | |
| 10/27 | A | Austintown-Fitch (3-7) | [1:1] | W | 12-0 |