| 8/29 | A | Central Catholic (12-3) | [3:8] | W | 35-23 | |
| 9/4 | A | Ursuline (8-6) | [4:11] | W | 24-14 | |
| 9/12 | A | Holy Name (8-4) | [4:11] | W | 28-0 | |
| 9/19 | A | University School (7-3) | [3:8] | W | 70-18 | |
| 9/25 | H | Bishop Watterson (6-5) | [3:9] | W | 27-7 | |
| 10/3 | H | Padua Franciscan (1-9) | [3:8] | W | 44-15 | |
| 10/9 | A | Notre Dame-Cathedral Latin (7-4) | [4:11] | W | 45-17 | |
| 10/16 | H | Lake Catholic (5-5) | [3:7] | W | 21-3 | |
| 10/23 | A | Walsh Jesuit (3-7) | [2:3] | W | 48-21 | |
| 10/31 | H | Archbishop Hoban (14-1) | [3:7] | W | 35-14 | |
| 11/6 | H | # Bowling Green (8-3) | [3:8] | W | 41-14 | |
| 11/13 | N | # Bay (10-2) | [3:8] | W | 31-10 | |
| 11/20 | N | # Central Catholic (12-3) | [3:8] | L | 30-31 | 2 ot |
| # - Ohio playoff game | ||||||