| 8/19 | A | River (8-5) | [VII:27] | W | 34-14 | |
| 8/28 | H | Toronto (5-6) | [VII:25] | W | 47-20 | |
| 9/3 | A | Harrison Central (4-7) | [V:17] | W | 27-0 | |
| 9/11 | H | Wheeling Central Catholic (WV) (7-3) | [VII] | W | 14-7 | |
| 9/18 | H | Cambridge (6-5) | [IV:15] | W | 45-14 | |
| 9/24 | A | Indian Creek (1-8) | [IV:15] | W | 41-19 | |
| 10/2 | H | St Clairsville (12-2) | [IV:15] | L | 16-28 | |
| 10/8 | A | Shadyside (11-2) | [VII:27] | W | 13-12 | |
| 10/15 | A | Union Local (5-5) | [IV:15] | W | 14-0 | |
| 10/23 | H | Martins Ferry (1-9) | [V:17] | W | 35-6 | |
| 10/30 | H | # Crestview (5-5) | [V:17] | W | 27-20 | |
| 11/6 | A | # Garfield (12-1) | [V:17] | L | 14-44 | |
| # - Ohio playoff game | ||||||