| 8/31 | H | Catholic Central (9-3) | [7:25] | L | 35-55 | |
| 9/6 | A | John Marshall (WV) (4-6) | [3:0] | W | 37-14 | |
| 9/14 | H | Shadyside (12-1) | [7:25] | L | 29-46 | |
| 9/21 | H | Edison (4-6) | [4:13] | W | 26-12 | |
| 9/27 | A | Buckeye Local (1-9) | [4:13] | W | 43-6 | |
| 10/4 | A | Indian Creek (6-4) | [4:13] | W | 31-13 | |
| 10/12 | H | St Clairsville (9-2) | [5:17] | W | 38-28 | |
| 10/19 | H | Harrison Central (5-5) | [5:15] | W | 28-15 | |
| 10/25 | A | Union Local (3-7) | [5:17] | W | 41-24 | |
| 11/2 | H | Martins Ferry (10-2) | [5:17] | L | 17-22 | |
| 11/8 | A | # Newark Catholic (11-2) | [6:21] | L | 0-29 | |
| # - Ohio playoff game | ||||||