| 8/20 | H | Indian Valley (7-3) | [IV:15] | L | 26-37 | |
| 8/27 | A | Salem (8-4) | [IV:13] | L | 35-62 | |
| 9/3 | A | Minerva (0-10) | [IV:13] | W | 56-7 | |
| 9/10 | H | East Liverpool (3-5) | [IV:13] | W | 48-0 | |
| 9/17 | H | Edison (7-4) | [V:17] | W | 27-21 | |
| 9/23 | A | Oak Glen (WV) (2-6) | [V] | C* | cancelled | |
| 9/24 | H | Lutheran East (5-6) | [V:17] | W | 47-16 | |
| 10/1 | H | Harrison Central (4-7) | [V:17] | W | 48-14 | |
| 10/8 | A | Indian Creek (1-8) | [IV:15] | W | 41-7 | |
| 10/15 | H | Martins Ferry (1-9) | [V:17] | W | 49-18 | |
| 10/22 | A | Wheeling Central Catholic (WV) (7-3) | [VII] | L | 7-21 | |
| 10/29 | A | # Glenville (9-4) | [IV:13] | L | 0-48 | |
| * - game does not count in OHSAA rankings | ||||||
| # - Ohio playoff game | ||||||