| 8/24 | H | Ironton (6-5) | [5:19] | W | 28-6 | |
| 8/31 | A | Bishop Hartley (9-3) | [3:11] | L | 20-51 | |
| 9/7 | H | Heath (4-6) | [5:19] | W | 48-0 | |
| 9/14 | A | Bishop Watterson (5-5) | [3:11] | W | 21-0 | |
| 9/21 | H | Jackson (7-4) | [3:11] | W | 33-14 | |
| 9/28 | A | Oak Hill (8-3) | [5:19] | W | 37-6 | |
| 10/5 | A | Waverly (9-2) | [4:16] | W | 49-0 | |
| 10/12 | H | Minford (6-4) | [5:20] | W | 49-0 | |
| 10/19 | H | Valley (4-6) | [6:23] | W | 37-6 | |
| 10/26 | A | Portsmouth West (6-5) | [5:20] | W | 28-7 | |
| 11/3 | H | # Portsmouth West (6-5) | [5:20] | W | 52-7 | |
| 11/10 | N | # Greeneview (10-2) | [5:20] | W | 35-13 | |
| 11/17 | N | # Madison (12-1) | [5:20] | W | 24-16 | |
| 11/24 | N | # Johnstown-Monroe (13-2) | [5:19] | L | 14-32 | |
| # - Ohio playoff game | ||||||