| 8/26 | A | Mifflin (5-5) | [2:7] | W | 42-41 | |
| 9/2 | H | Centennial (3-7) | [3:11] | W | 53-13 | |
| 9/9 | A | East (1-9) | [4:14] | W | 44-14 | |
| 9/16 | A | Africentric Early College (2-8) | [7:27] | W | 70-32 | |
| 9/23 | H | Walnut Ridge (6-4) | [2:7] | W | 53-44 | |
| 9/30 | A | Marion-Franklin (3-7) | [3:11] | W | 21-18 | |
| 10/7 | H | Independence (5-5) | [3:11] | W | 44-30 | |
| 10/14 | A | South (4-6) | [3:11] | W | 56-14 | |
| 10/21 | A | Eastmoor Academy (8-3) | [3:11] | L | 22-25 | |
| 10/28 | H | Briggs (2-8) | [2:7] | W | 44-25 | |
| 11/4 | A | # New Albany (9-4) | [2:7] | L | 0-31 | |
| # - Ohio playoff game | ||||||