| Date | H/A | Opponent | Div. | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/22 | H | Fort Frye (8-1) | [VI:23] | W | 35-7 | |
| 8/29 | H | Meadowbrook (4-6) | [V:19] | W | 51-21 | |
| 9/5 | A | Bellaire (3-7) | [V:17] | W | 40-0 | |
| 9/12 | H | Buckeye Local (2-8) | [V:17] | W | 56-0 | |
| 9/19 | A | Monroe Central (5-5) | [VI:23] | W | 48-7 | |
| 9/26 | H | George Washington (WV) (7-2) | [II] | L | 14-17 | |
| 10/2 | A | Wheeling Central Catholic (WV) (6-2) | [VII] | W | 43-14 | |
| 10/10 | H | Linsly (WV) (3-6) | [VII] | W | 34-7 | |
| 10/17 | N | Independence (WV) (8-1) | [IV] | L | 21-42 | |
| 10/24 | A | Union Local (8-3) | [V:19] | W | 34-0 | |
| 11/7 | H | # Portsmouth (8-3) | [V:19] | |||
| # - Ohio playoff game | ||||||