| Date | H/A | Opponent | Div. | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/21 | A | St Francis DeSales (8-3) | [II:7] | L | 7-31 | |
| 8/28 | A | Louisville (9-2) | [II:7] | W | 43-10 | |
| 9/5 | H | Bishop Watterson (9-0) | [II:7] | L | 10-41 | |
| 9/11 | A | Youngstown (3-6) | [II:5] | W | 25-9 | |
| 9/18 | A | Warren G Harding (4-6) | [II:5] | W | 40-7 | |
| 9/24 | A | Farrell (PA) (7-2) | [VII] | W | 24-13 | |
| 10/1 | H | Steubenville (8-2) | [III:11] | W | 44-40 | |
| 10/9 | A | Walsh Jesuit (7-2) | [II:5] | L | 7-45 | |
| 10/16 | H | Shaw (2-8) | [V:17] | W | 41-8 | |
| 10/23 | A | Cardinal Mooney (8-3) | [V:17] | L | 21-28 | |
| 10/30 | H | # Lake Catholic (6-5) | [III:9] | W | 34-20 | |
| 11/6 | A | # South (10-0) | [III:9] | |||
| # - Ohio playoff game | ||||||