| 8/29 | H | Nelsonville-York (1-9) | [5:17] | L | 20-26 | |
| 9/4 | A | Belpre (8-3) | [7:25] | W | 34-0 | |
| 9/11 | H | South Gallia (6-5) | [7:25] | W | 44-12 | |
| 9/18 | A | Waterford (5-5) | [7:25] | W | 29-18 | |
| 9/25 | H | Miller (6-4) | [7:25] | W | 56-14 | |
| 10/2 | A | Wahama (WV) (4-6) | [7:0] | W | 46-14 | |
| 10/9 | H | Southern (4-6) | [7:25] | W | 41-14 | |
| 10/16 | H | Eastern (2-8) | [7:25] | W | 75-12 | |
| 10/23 | A | Alexander (10-2) | [5:17] | L | 13-42 | |
| 10/30 | A | Federal Hocking (0-10) | [7:25] | W | 50-0 | |
| 11/6 | H | # Shadyside (4-7) | [7:25] | W | 17-14 | |
| 11/13 | N | # Caldwell (11-2) | [7:25] | L | 19-40 | |
| # - Ohio playoff game | ||||||