| 8/29 | A | Nelsonville-York (7-4) | [6:21] | W | 34-14 | |
| 9/5 | H | Belpre (8-3) | [6:21] | W | 57-0 | |
| 9/12 | A | South Gallia (5-5) | [7:25] | W | 41-12 | |
| 9/19 | H | Waterford (2-8) | [7:25] | W | 69-0 | |
| 9/26 | A | Miller (1-9) | [7:25] | W | 62-6 | |
| 10/3 | H | Wahama (WV) (6-4) | [6:0] | W | 42-0 | |
| 10/10 | A | Southern (4-6) | [7:25] | W | 40-6 | |
| 10/17 | A | Eastern (5-5) | [7:25] | W | 65-6 | |
| 10/24 | H | Alexander (5-5) | [5:17] | W | 37-6 | |
| 10/31 | H | Federal Hocking (2-8) | [6:21] | W | 60-12 | |
| 11/8 | H | # Symmes Valley (6-5) | [7:25] | W | 55-8 | |
| 11/15 | N | # Caldwell (11-1) | [7:25] | W | 14-10 | |
| 11/22 | N | # Shadyside (11-1) | [7:25] | W | 31-21 | |
| 11/29 | N | # St Paul (13-2) | [7:23] | L | 13-41 | |
| # - Ohio playoff game | ||||||