| 8/26 | A | Wellsville (5-5) | [7:25] | W | 36-16 | |
| 9/2 | A | Bridgeport (1-9) | [7:27] | W | 54-8 | |
| 9/9 | A | Sebring McKinley (3-7) | [7:25] | W | 43-22 | |
| 9/16 | H | Catholic Central (5-5) | [6:23] | W | 18-7 | |
| 9/23 | H | Shadyside (8-3) | [7:27] | L | 30-31 | |
| 9/30 | A | Conotton Valley (3-7) | [7:25] | W | 62-0 | |
| 10/7 | H | Beallsville (0-10) | [7:27] | W | 66-7 | |
| 10/14 | H | River (10-1) | [6:23] | L | 31-38 | |
| 10/21 | H | Edison (3-7) | [5:19] | W | 47-22 | |
| 10/28 | A | Madonna (WV) (2-8) | [7:0] | W | 57-7 | |
| 11/5 | A | # John F Kennedy (14-1) | [7:25] | L | 0-38 | |
| # - Ohio playoff game | ||||||