| 9/1 | A | Dulaney (0-1) | W | 42-0 | ||
| 9/8 | A | William Penn (DE) (0-1) | W | 14-7 | ||
| 9/14 | A | Polytechnic (0-1) | W | 36-0 | ||
| 9/29 | H | Taft (OH) (8-2) | [4:16] | C* | cancelled | |
| 10/6 | H | Patterson (0-1) | W | 33-20 | ||
| 10/12 | A | City College (0-1) | W | 54-6 | ||
| 10/18 | H | Douglass (0-1) | W | 41-0 | ||
| 10/22 | H | Dunbar (1-0) | L | 8-34 | ||
| 10/25 | A | Digital Harbor (0-1) | W | 32-6 | ||
| 11/2 | H | Edmonson / Westside (0-1) | W* | 48-14 | ||
| * - game does not count in OHSAA rankings | ||||||