| 8/29 | H | Meadowbrook (6-4) | [4:13] | W | 34-20 | |
| 9/5 | H | Monroe Central (8-3) | [6:21] | W | 21-0 | |
| 9/12 | H | Bellaire (3-7) | [6:21] | W | 20-7 | |
| 9/19 | A | Shenandoah (1-9) | [6:21] | W | 48-0 | |
| 9/26 | A | Toronto (8-3) | [7:23] | W | 33-6 | |
| 10/3 | A | Beallsville (1-9) | [7:25] | W | 50-0 | |
| 10/10 | H | Wheeling Central Catholic (WV) (4-6) | [7:0] | W | 33-7 | |
| 10/17 | H | Union Local (4-6) | [5:17] | W | 35-0 | |
| 10/24 | A | Bridgeport (6-4) | [7:25] | W | 42-13 | |
| 11/8 | H | # Danville (6-5) | [7:25] | W | 27-24 | |
| 11/15 | N | # Paint Valley (8-4) | [7:25] | W | 41-15 | |
| 11/22 | N | # Trimble (13-1) | [7:25] | L | 21-31 | |
| # - Ohio playoff game | ||||||