| 8/25 | H | Royal Imperial Collegiate (ON) (1-7) | [7:0] | W | 50-0 | |
| 9/1 | H | Lancaster (4-6) | [1:3] | W | 34-14 | |
| 9/8 | H | Cardinal Mooney (7-5) | [4:13] | W | 28-7 | |
| 9/15 | N | Indianapolis Bishop Chatard (IN) (5-5) | [4:0] | L | 7-42 | |
| 9/22 | A | Covington Catholic (KY) (10-0) | [2:0] | L | 7-35 | |
| 9/29 | A | St Charles (1-9) | [2:7] | W | 31-0 | |
| 10/6 | A | Edgewood (8-2) | [2:8] | W | 28-3 | |
| 10/13 | A | Bishop Hartley (11-2) | [3:11] | L | 21-23 | |
| 10/20 | H | Winton Woods (13-2) | [2:8] | L | 7-42 | |
| 10/27 | H | Bishop Watterson (2-8) | [3:11] | W | 41-7 |