| 8/25 | A | Walsh Jesuit (4-5) | [3:9] | W | 28-21 | |
| 9/1 | H | Westerville South (8-3) | [1:3] | W | 50-37 | |
| 9/8 | H | Covington Catholic (KY) (4-6) | [2:0] | W | 42-19 | |
| 9/16 | A | Riverside (9-2) | [1:1] | L | 22-31 | |
| 9/22 | H | Dunbar (6-4) | [3:12] | W | 35-6 | |
| 9/29 | H | St Charles (7-4) | [2:7] | W | 23-7 | |
| 10/7 | A | Bishop Watterson (9-4) | [3:10] | W | 28-23 | |
| 10/13 | A | Archbishop Moeller (9-2) | [1:4] | L | 28-35 | |
| 10/20 | H | Whitehall-Yearling (2-8) | [2:7] | W | 34-26 | |
| 10/27 | A | Ironton (10-2) | [4:15] | L | 21-28 | |
| 11/3 | H | # Dover (7-4) | [2:7] | W | 30-10 | |
| 11/10 | N | # Brookhaven (10-2) | [2:7] | W | 28-25 | |
| 11/17 | N | # Marysville (13-1) | [2:7] | L | 29-35 | |
| # - Ohio playoff game | ||||||