| 8/28 | A | Clinton-Massie (9-1) | [IV:16] | L | 32-42 | |
| 9/4 | H | Badin (7-1) | [III:12] | L | 12-14 | |
| 9/11 | H | Bishop Fenwick (1-7) | [III:12] | W | 49-13 | |
| 9/18 | A | Carroll (3-6) | [III:12] | W | 48-0 | |
| 9/25 | A | Archbishop McNicholas (5-3) | [IV:16] | W | 28-7 | |
| 10/1 | H | Chaminade Julienne (3-5) | [III:12] | W | 49-21 | |
| 10/16 | H | # Dunbar (4-3) | [III:12] | W | 35-13 | |
| 10/23 | A | # Trotwood-Madison (4-1) | [III:12] | W | 42-0 | |
| 10/30 | A | # Badin (7-1) | [III:12] | W | 20-3 | |
| 11/6 | A | # Ross (8-2) | [III:12] | W | 35-21 | |
| 11/13 | N | # St Francis DeSales (9-2) | [III:11] | L | 13-23 | |
| # - Ohio playoff game | ||||||