| 8/24 | A | Kettering Fairmont (7-4) | [1:3] | L | 12-13 | |
| 9/1 | H | Thurgood Marshall (6-4) | [3:12] | W | 35-0 | |
| 9/8 | H | Xenia (2-8) | [2:8] | W | 42-19 | |
| 9/15 | H | Carroll (1-9) | [2:8] | W | 58-0 | |
| 9/22 | A | Bishop Fenwick (6-4) | [4:16] | W | 46-22 | |
| 9/29 | A | Roger Bacon (4-6) | [4:16] | W | 42-0 | |
| 10/6 | H | Purcell Marian (2-8) | [5:20] | W | 56-6 | |
| 10/13 | A | Badin (5-5) | [3:12] | W | 35-0 | |
| 10/20 | H | Archbishop McNicholas (6-4) | [3:12] | W | 28-14 | |
| 10/27 | A | Chaminade Julienne (9-4) | [3:12] | W | 34-6 | |
| 11/3 | H | # Chaminade Julienne (9-4) | [3:12] | L | 28-49 | |
| # - Ohio playoff game | ||||||