| 8/27 | A | Kettering Fairmont (1-9) | [1:3] | W | 27-8 | |
| 9/2 | A | Thurgood Marshall (5-5) | [3:12] | W | 51-15 | |
| 9/9 | A | Xenia (3-7) | [2:8] | W | 49-7 | |
| 9/16 | A | Carroll (4-6) | [3:12] | W | 49-0 | |
| 9/23 | H | Bishop Fenwick (6-4) | [4:16] | W | 52-3 | |
| 9/30 | H | Roger Bacon (3-7) | [5:20] | W | 65-13 | |
| 10/7 | A | Purcell Marian (3-7) | [6:24] | W | 56-13 | |
| 10/14 | H | Badin (2-8) | [4:16] | W | 48-0 | |
| 10/22 | A | Archbishop McNicholas (4-6) | [3:12] | W | 35-3 | |
| 10/28 | H | Chaminade Julienne (6-4) | [4:16] | W | 51-3 | |
| 11/4 | H | # Indian Hill (9-2) | [4:16] | W | 54-28 | |
| 11/11 | N | # Clinton-Massie (10-2) | [4:16] | W | 28-0 | |
| 11/18 | N | # Wyoming (12-1) | [4:16] | W | 35-7 | |
| 11/25 | N | # Bishop Hartley (13-2) | [4:14] | L | 7-14 | |
| # - Ohio playoff game | ||||||