| 8/20 | A | Perry (10-3) | [IV:13] | L | 6-26 | |
| 8/27 | H | Amherst (0-10) | [II:6] | W | 49-14 | |
| 9/3 | H | Holy Name (7-6) | [III:10] | W | 28-7 | |
| 9/10 | A | Chardon (16-0) | [III:9] | L | 7-28 | |
| 9/17 | A | Madison (1-9) | [II:5] | W | 45-0 | |
| 9/24 | H | Mayfield (2-8) | [II:5] | W | 57-7 | |
| 10/1 | A | North (4-7) | [II:5] | W | 42-14 | |
| 10/9 | H | Martinsburg (WV) (9-1) | [II] | L | 33-45 | |
| 10/15 | A | Kenston (11-2) | [III:9] | L | 14-21 | |
| 10/22 | H | South (8-4) | [II:5] | W | 14-7 | |
| 10/29 | H | # Brush (5-5) | [II:5] | W | 56-15 | |
| 11/5 | A | # Benedictine (8-3) | [II:5] | L | 12-31 | |
| # - Ohio playoff game | ||||||