| 8/26 | H | Meadville (2-1) | W | 34-7 | ||
| 9/1 | A | Cathedral Prep (10-0) | [2:0] | L | 0-38 | |
| 9/9 | H | General McLane (0-3) | W | 56-6 | ||
| 9/15 | A | Fort LeBoeuf (2-4) | W | 42-3 | ||
| 9/23 | A | Trinity (OH) (5-5) | [6:21] | W | 49-0 | |
| 9/29 | A | Franklin (2-1) | W | 62-27 | ||
| 10/6 | A | McDowell (5-6) | [1:0] | L | 22-30 | |
| 10/12 | H | Brashear (3-2) | W | 62-9 | ||
| 10/20 | A | Lakeside (OH) (4-6) | [2:5] | W | 35-6 | |
| 10/28 | H | West Toronto Prep (via Silverthorn CI) (ON) (1-3) | [3:0] | W | 55-6 | |
| 11/3 | N | McDowell (5-6) | [1:0] | W* | 35-34 | |
| * - game does not count in OHSAA rankings | ||||||