| 8/20 | H | Carmel (IN) (2-0) | L | 38-49 | ||
| 8/28 | A | Archbishop Moeller (OH) (11-4) | [I:4] | C* | cancelled | |
| 9/3 | H | St Rita (IL) (1-0) | L | 14-27 | ||
| 9/10 | H | La Salle (OH) (7-6) | [II:8] | L | 27-48 | |
| 9/17 | A | Male (Louisville) (3-0) | L | 10-24 | ||
| 9/24 | N | St Xavier (Louisville) (9-1) | [I] | L | 28-35 | |
| 10/1 | A | St Xavier (OH) (10-3) | [I:4] | W | 33-32 | |
| 10/8 | A | Ballard (0-2) | W | 20-17 | ||
| 10/15 | H | St Mary's (St Louis) (MO) (7-1) | [V] | L | 19-22 | |
| 10/22 | H | Eastern (Louisville) (0-1) | W | 56-21 | ||
| * - game does not count in OHSAA rankings | ||||||