| 8/17 | A | DeSales (Louisville) (1-0) | L | 16-19 | ||
| 8/31 | H | Bowling Green (1-0) | L | 21-24 | ot | |
| 9/7 | H | Fairdale (0-1) | W | 61-6 | ||
| 9/14 | H | Central (Louisville) (0-1) | W | 20-19 | ||
| 9/21 | H | Pleasure Ridge Park (0-2) | W | 45-13 | ||
| 9/28 | N | Trinity (Louisville) (4-6) | [1:0] | W | 21-7 | |
| 10/5 | H | DuPont Manual (0-1) | W | 25-7 | ||
| 10/12 | A | Male (Louisville) (1-1) | W | 28-13 | ||
| 10/19 | A | Butler (Louisville) (0-1) | W | 14-6 | ||
| 10/26 | A | St Xavier (OH) (5-6) | [1:4] | L | 7-34 |