| 8/18 | H | Lockland (OH) (5-6) | [VII:28] | W | 42-6 | |
| 9/1 | H | Sayre (2-0) | L | 0-14 | ||
| 9/8 | A | Dayton (2-1) | L | 6-22 | ||
| 9/15 | H | Newport (4-1) | L | 14-16 | ||
| 9/22 | H | Pendleton County (Falmouth) (0-3) | W | 61-12 | ||
| 9/29 | A | Bellevue (4-6) | [VII] | W | 56-12 | |
| 10/6 | A | Trimble County (1-3) | W | 41-6 | ||
| 10/13 | H | Bishop Brossart (5-5) | [VII] | W | 20-7 | |
| 10/20 | H | Holy Cross (Covington) (5-5) | [VI] | W | 38-13 | |
| 10/27 | A | Paris (4-1) | L* | 26-50 | ||
| * - game does not count in OHSAA rankings | ||||||