| 8/21 | N | St Xavier (Louisville) (0-1) | W | 24-14 | ||
| 8/27 | A | Boone County (5-6) | W | 38-13 | ||
| 9/4 | A | Ryle (Union) (2-1) | L | 20-25 | ||
| 9/11 | H | St Francis DeSales (OH) (7-4) | [3:10] | L | 7-33 | |
| 9/17 | A | Beechwood (13-2) | L | 0-26 | ||
| 10/2 | H | Highlands (14-1) | L | 7-45 | ||
| 10/9 | H | Conner (0-3) | W | 10-0 | ||
| 10/15 | A | Holmes (Covington) (1-2) | W | 34-31 | ||
| 10/23 | H | Scott (Covington) (0-2) | W | 39-7 | ||
| 10/29 | A | Dixie Heights (2-2) | L | 7-41 | ||
| 11/5 | A | Harrison County (1-1) | L* | 16-21 | ||
| * - game does not count in OHSAA rankings | ||||||