| 8/18 | A | DuPont Manual (8-2) | [I] | L | 0-26 | |
| 8/26 | H | St Xavier (Louisville) (7-3) | [I] | L | 6-21 | |
| 9/1 | H | Butler (Louisville) (0-3) | W | 34-0 | ||
| 9/8 | H | La Salle (OH) (4-7) | [II:8] | L | 0-21 | |
| 9/15 | A | Bullitt East (2-1) | L | 0-13 | ||
| 9/22 | A | Central Hardin (0-2) | W | 26-17 | ||
| 9/29 | H | Elizabethtown (0-1) | W | 60-7 | ||
| 10/13 | A | Christian Academy-Louisville (3-0) | L | 6-13 | ||
| 10/20 | H | LaRue County (0-1) | W | 50-7 | ||
| 10/27 | H | W.E.B. DuBois Academy (0-1) | W* | 30-0 | ||
| * - game does not count in OHSAA rankings | ||||||