| 8/27 | A | Martins Ferry (OH) (1-9) | [V:17] | W | 27-14 | |
| 9/4 | H | Fairmont Senior (0-1) | W | 31-22 | ||
| 9/11 | A | Cardinal Mooney (OH) (1-9) | [V:17] | W | 35-21 | |
| 9/17 | A | St Clairsville (OH) (12-2) | [IV:15] | L | 14-35 | |
| 9/17 | A | Princeton Senior (0-1) | C* | cancelled | ||
| 9/24 | A | Steubenville (OH) (9-3) | [III:9] | L | 17-26 | |
| 10/1 | H | McGuffey (PA) (0-1) | W | 26-21 | ||
| 10/8 | A | Canton Central Catholic (OH) (4-7) | [VI:21] | W | 41-20 | |
| 10/15 | A | Dover (OH) (12-1) | [III:9] | L | 0-42 | |
| 10/23 | H | Louisville (OH) (2-8) | [III:9] | L | 14-20 | |
| 10/29 | A | Hollidaysburg (PA) (1-1) | L* | 14-19 | ||
| * - game does not count in OHSAA rankings | ||||||