| 8/25 | H | James Monroe (1-0) | L | 32-45 | ||
| 9/1 | H | Perry Traditional Academy (PA) (1-7) | W | 20-18 | ||
| 9/8 | H | St Clairsville (OH) (9-3) | [IV:15] | L | 24-60 | |
| 9/15 | H | Midland Trail (0-1) | W | 47-6 | ||
| 9/22 | H | University Prep (co-op) (PA) (7-3) | [II] | L | 17-36 | |
| 9/30 | H | Maret School (DC) (1-0) | L | 28-64 | ||
| 10/6 | H | Shadyside (OH) (3-8) | [VII:27] | W | 48-14 | |
| 10/13 | A | Martins Ferry (OH) (5-6) | [VI:23] | W | 22-16 | |
| 10/20 | A | Harbor Creek (PA) (1-2) | W | 49-20 | ||
| 11/4 | A | Williamstown (10-0) | [VI] | L* | 21-65 | |
| * - game does not count in OHSAA rankings | ||||||