| 8/25 | H | Catholic Central (OH) (7-4) | [6:23] | L | 14-35 | |
| 9/8 | A | East Hardy (10-0) | [7:0] | L | 7-10 | |
| 9/15 | H | Williamstown (5-4) | [6:0] | W | 28-23 | |
| 9/22 | H | Magnolia (4-6) | [6:0] | W | 29-27 | |
| 9/30 | A | Linsly (9-2) | [6:0] | L | 13-21 | |
| 10/6 | H | Shadyside (OH) (7-4) | [6:23] | W | 27-26 | |
| 10/13 | A | Martins Ferry (OH) (7-4) | [5:19] | L | 19-38 | |
| 10/21 | H | University Prep (co-op) (PA) (4-6) | [2:0] | W | 27-6 | |
| 10/28 | A | Madonna (8-2) | [7:0] | W | 50-0 | |
| 11/3 | H | Oak Glen (2-8) | [4:0] | W* | 65-7 | |
| * - game does not count in OHSAA rankings | ||||||