| 8/18 | A | Trimble (6-5) | [VI:23] | L | 12-14 | |
| 8/25 | H | Newark Catholic (3-7) | [VI:23] | W | 21-9 | |
| 9/1 | A | Liberty Union (1-9) | [V:19] | W | 47-19 | |
| 9/8 | H | River Valley (0-10) | [V:19] | W | 54-0 | |
| 9/14 | H | Bexley (4-7) | [III:11] | W | 26-13 | |
| 9/22 | A | Meigs (2-8) | [V:19] | W | 47-14 | |
| 9/29 | H | Wellston (4-6) | [V:19] | W | 46-12 | |
| 10/6 | A | Alexander (2-8) | [V:19] | W | 33-0 | |
| 10/13 | H | Vinton County (9-2) | [IV:15] | L | 7-13 | |
| 10/20 | A | Athens (6-5) | [III:11] | L | 13-19 | |
| 10/27 | H | # Bellaire (5-6) | [VI:23] | W | 20-12 | |
| 11/3 | A | # West Jefferson (12-2) | [VI:23] | L | 7-29 | |
| # - Ohio playoff game | ||||||